Effect of Recombinant Human Bone Morphogenetic Protein-2 With an Absorbable Collagen Sponge on Stability of Dental Implant: (Split Mouth Randomized Clinical Trial Study.

Inclusion Criteria:

* Patients have good oral hygiene.
* Systemic healthy individuals ,Age more than18 years.
* Healed edentulous area for at least 6 months after tooth extraction (delayed implant protocol).
* Patients have at least two missing teeth in the jaw (canine to 1st molar area) indicated for the dental implant.

Exclusion Criteria:

* Presence of systemic diseases preventing implantation.
* Previous implantation or augmentation of the same region.
* The need for additional bone augmentation procedures (such as maxillary sinus augmentation)
* Partial or total edentulous ridge associated with a severe knife-edge ridge .
* Acute infection or any pathological lesion a the implant site.
* Allergy to one of the materials to be used during operation.
* Pregnancy.
* Radiation therapy, bisphosphonate drugs , Osteoradionecrosis.